I’m one of those people that if I’ve changed characters a bunch I have to restart my DDO client before entering a quest or wilderness area or face a possible game crash. It’s really annoying but it’s something I’ve learned to live.
I recently came across this forum post gave a little help with the subject. I followed the directions and now my game crashes a bit less. I find that now I crash half as much as before, which is still annoying, but it’s a step forward.
Part of the problem could be that I run DDO on an older machine and my old operating system can’t handle all the memory leaks that the game has. Many of my friends in the game have newer computers and they hardly crash at all.
Hope this helps.